Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Intensive PK/PD profile of plasma pegvaliase and Phe concentrations in the open‐label phase III PRISM‐2 study in adults with PKU who received pegvaliase 20 or 40 mg/day and achieved at least a 20% decrease from baseline in blood Phe levels. Intensive PK/PD sampling was performed during week 1 and weeks 5–6 in part 3 of PRISM‐2 (N = 57). Data are mean ± standard error. PD, pharmacodynamic; Phe, phenylalanine; PK, pharmacokinetic; PKU, phenylketonuria
