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. 2021 Oct 7;15:4243–4255. doi: 10.2147/DDDT.S332623

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© 2021 Wang et al.

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Changes in CEUS values and effects of curcumin at 24h. (a–e) CEUS values in renal cortex. Levels of AUC (a), PI (b), DT/2 (c) and DS (d) in the CLP group were significantly decreased compared with the sham group, AS (e) levels were significantly increased compared with the sham group. Curcumin treatment significantly increased levels of AUC, PI and DT/2 compared with the CLP group and had no effect on the increase of DS or the decrease of AS. (A–C) CEUS values in renal medulla. Levels of DT/2 (A), DS (B), AUC (C) in CLP group were significantly decreased compared with the sham group. Curcumin treatment had no effect on the decrease of DT/2, DS, AUC. *P < 0.05 compared with sham; ^#P < 0.05 compared with CLP (n = 8 per group).