Table 3.

Hazard ratios and 95% confidence intervals for the incidence of myocardial infarction, stroke, and all‐cause death during follow‐up according to insulin use among people with type 2 diabetes (diabetes duration <5 years)

Group	Events (n)	Follow‐up duration (person‐years)	Incidence rate (per 1000 person‐years)	Unadjusted	Age and sex‐adjusted	Multivariable adjusted*
Myocardial infarction
Type 2 diabetes, insulin non‐user † (n = 14,397)	445	109,030.08	4.08144	1 (Ref.)	1 (Ref.)	1 (Ref.)
Type 2 diabetes, insulin user † (n = 1,370)	81	9,247.07	8.75953	2.141 (1.690, 2.713)	2.123 (1.675, 2.690)	1.914 (1.502, 2.441)
P‐value				<0.0001	<0.0001	<0.0001
Stroke
Type 2 diabetes, insulin non‐user † (n = 14,397)	673	108,423.56	6.20710	1 (Ref.)	1 (Ref.)	1 (Ref.)
Type 2 diabetes, insulin user † (n = 1,370)	110	9,180.05	11.98250	1.926 (1.575, 2.357)	1.89 (1.545, 2.312)	1.676 (1.363, 2.060)
P‐value				<0.0001	<0.0001	<0.0001
All‐cause death
Type 2 diabetes, insulin non‐user † (n = 14,397)	1,226	110,508.11	11.09420	1 (Ref.)	1 (Ref.)	1 (Ref.)
Type 2 diabetes, insulin user † (n = 1,370)	318	9,498.35	33.47950	3.020 (2.670, 3.417)	2.906 (2.569, 3.288)	2.535 (2.232, 2.880)
P‐value				<0.0001	<0.0001	<0.0001

^*Adjusted for age, sex, monthly income, and Charlson Comorbidity Index.

^† Only those with diabetes duration of <5 years were included among people with type 2 diabetes.

Bold indicates statistically significant values among the hazard ratios.