Table 6.
Univariate and multivariate analyses of the onset of impaired fasting glucose among women
| Normal | Normal ALT levels and fatty liver disease | High ALT levels and fatty liver disease | P for trend | ||
|---|---|---|---|---|---|
| Nonalcoholic group | Incident rate (%) | 80/3,588 (2.2%) | 26/280 (9.3%) | 35/235 (14.9%) | |
| Crude HR (95% CI) | 1.00 | 4.6 (2.96–7.17) | 8.26 (5.54–12.29) | <0.01 | |
| Adjusted HR* (95% CI) | 1.00 | 1.67 (1.03–2.7) | 1.03 (0.6–1.77) | 0.08 | |
| Alcoholic group | Incident rate (%) | 1/15 (6.7%) | 1/11 (9.1%) | ||
| Crude HR (95% CI) | 1.00 | 4.11 (0.57–29.61) | 9.82 (1.36–71.19) | 0.03 | |
| Adjusted HR (95% CI) | 1.00 | 0.93 (0.11–7.9) | 1.32 (0.15–11.61) | 0.96 |
*
Multivariate Cox proportional hazards regression analysis was adjusted for age (years), BMI (kg/m2), SBP (mmHg), FPG (mM), Cre (µM), UA (µM), TC (mM), TG (mM), exercise habits, snacking habits, and family history of diabetes. Differences were considered statistically significant for P < 0.05. HR, hazard ratio; CI, confidence interval; ALT, alanine aminotransferase; BMI, body mass index; SBP, systolic blood pressure; FPG, fasting plasma glucose; Cre, creatinine; UA, uric acid; TC, total cholesterol; TG, triglycerides.