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. 2021 Sep 29;15(9):e0009709. doi: 10.1371/journal.pntd.0009709

Table 3. Diarrhoeal pathogens in 429 children with and without diarrhoea divided into two age groups: infants (0–11 months) and young children (12–59 months).

0–11 months 12–59 months
Total
n (%)
No diarrhoea
n (%)
Diarrhoea
n (%)
Diarrhoea versus No diarrhoea
OR (95% CI) p-value
No diarrhoea
n (%)
Diarrhoea
n (%)
Diarrhoea versus No diarrhoea
OR (95% CI) p-value
Total 429 (100) 94 (48.4) 99 (51.6) 107 (45.1) 129 (54.9)
Any pathogen 422 (98.8) 91 (97.8) 98 (99.0) 2.2 (0.2–24.2) 0.612 103 (97.2) 128 (99.2) 3.7 (0.4–36.4) 0.330
Any bacteria a 409 (95.8) 89 (95.7) 95 (96.0) 0.5 (0.1–3.0) 0.684 98 (92.5) 126 (97.7) 3.9 (0.8–19.5) 0.144
Campylobacter 225 (53.1) 49 (52.7) 47 (47.5) 0.8 (0.4–1.4) 0.380 58 (54.7) 71 (55.0) 1.0 (0.6–1.7) 0.963
EAEC 272 (64.2) 73 (78.5) 66 (66.7) 0.5 (0.3–1.0) 0.035 60 (56.6) 72 (55.8) 0.9 (0.6–1.6) 0.825
EHEC 6 (1.4) 1 (1.1) 0 (0.0) NA 0.479 4 (3.8) 1 (0.8) 2.0 (0.2–1.8) 0.176
EIEC/Shigella 98 (23.1) 14 (15.1) 14 (14.1) 0.9 (0.4–2.0) 0.809 22 (20.8) 48 (37.2) 2.2 (1.2–4.0) 0.007
EPEC 266 (62.7) 58 (62.4) 65 (65.7) 1.1 (0.6–2.0) 0.782 67 (63.2) 75 (58.1) 0.8 (0.5–1.3) 0.365
ETEC 213 (50.2) 48 (51.6) 56 (56.6) 1.2 (0.7–2.1) 0.597 41 (38.7) 68 (52.7) 1.7 (1.0–2.9) 0.038
Salmonella 11 (2.6) 5 (5.4) 3 (3.0) 0.5 (0.1–2.3) 0.483 1 (0.9) 2 (1.6) 1.6 (1.4–18.3) 1.000
V. cholerae 2 (0.5) 0 (0.0) 1 (1.0) NA 1.000 0 (0.0) 1 (0.8) NA 1.000
Yersinia 3 (0.7) 1 (1.1) 1 (1.0) 0.9 (0.1–14.9) 1.000 0 (0.0) 1 (0.8) NA 1.000
Any viruses b 233 (54.6) 51 (54.8) 65 (65.7) 1.7 (0.9–3.2) 0.092 38 (35.8) 78 (60.5) 2.8 (1.6–4.9) <0.001
Adenovirus 40, 41 73 (18.4) 20 (21.5) 17 (17.2) 0.8 (0.4–1.6) 0.456 12 (11.3) 23 (17.8) 1.7 (0.8–3.5) 0.186
Astrovirus 40 (10.1 4 (4.3) 16 (16.2) 4.4 (1.4–13.6) 0.007 6 (5.7) 14 (10.9) 2.0 (0.7–5.4) 0.172
Norovirus GI 21 (5.3) 8 (8.6) 5 (5.1) 0.5 (0.2–1.8) 0.333 2 (1.9) 6 (4.7) 2.5 (0.5–12.5) 0.305
Norovirus GII 73 (18.4) 12 (12.9) 28 (28.3) 2.7 (1.3–5.8) 0.008 8 (7.5) 25 (19.4) 2.9 (1.2–6.8) 0.011
Rotavirus A 93 (23.4) 22 (23.7) 24 (24.2) 1.0 (0.5–2.0) 0.903 18 (17.0) 29 (22.5) 1.4 (0.7–2.7) 0.338
Sapovirus 29 (7.3) 6 (6.5) 8 (8.1) 1.3 (0.4–3.9) 0.654 4 (3.8) 11 (8.5) 2.3 (0.7–7.5) 0.151
Any parasites c 217 (50.8) 35 (37.6) 40 (40.4) 1.4 (0.6–2.0) 0.653 60 (56.6) 80 (62.0) 1.2 (0.7–2.0) 0.503
Cryptosporidium sp. 59 (13.8) 10 (10.8) 21 (21.2) 2.3 (1.0–5.1) 0.045 7 (6.6) 21 (16.3) 2.7 (1.0–6.6) 0.026
D. fragilis 159 (37.3) 4 (4.3) 5 (5.1) 1.2 (0.3–4.7) 1.000 16 (15.1) 18 (14.0) 0.9 (0.4–1.8) 0.724
E. histolytica 43 (10.7) 1 (1.1) 0 (0.0) NA 0.487 2 (1.9) 0 (0.0) NA 0.198
G. duodenalis 3 (0.7) 24 (25.8) 21 (21.2) 0.8 (0.4–1.5) 0.476 48 (45.3) 64 (49.6) 1.1 (0.7–1.9) 0.599

Data is missing, n (%)

a) 5 (1.2)

b) 32 (7.5)

c) 3 (0.7)

OR = odds ratio (logistic regression); CI = confidence interval; bolding indicates statistically significant at p<0.05 (Pearson χ2 test or Fisher´s exact test); NA = not applicable