Peters 2013.

Trial name or title	Radiographic progression of infiltrated caries lesions in vivo
Methods	Split‐mouth randomised controlled trial Funded by DMG, Hamburg Drop‐out 23% after 12 months
Participants	12 participants (aged 18 to 24 years) with DMFT of 3 or more; having at least two early caries lesions in proximal posterior tooth surfaces; lesions needed to be visible on radiograph Exclusion criteria: current participation in another clinical study; medically compromised subjects; hyposalivation; pregnancy; allergic to methylmethacrylates or latex; symptomatic teeth
Interventions	Group 1: resin infiltration (Icon, DMG) plus oral hygiene, diet counselling, fluoride varnish Group 2: control (sham treatment) plus oral hygiene, diet counselling, fluoride varnish
Outcomes	Lesion progression according to pairwise reading and DSR.
Starting date	March 2013, estimated completion December 2016
Contact information	Mathilde Peters, University of Michigan (mcpete@umich.edu)
Notes	ClinicalTrials.gov Identifier: NCT01584024

DMFT: decayed, missing or filled teeth (primary/permanent);DSR: digital subtraction radiography.