Figure 4.

Treatment with Jie-Yu-He-Huan capsule prevents alterations in the hypothalamic–pituitary–adrenal axis hormone concentrations in serum caused by chronic restraint stress. (a) Corticotropin-releasing hormone (CRH) levels. (b) Adrenocorticotropic (ACTH) hormone levels. (c) Corticosterone (CORT) levels. ^∗p < 0.05 compared to the control group, ^#p < 0.05 compared to the model group, ^##p < 0.01 compared to the model group, and ^###p < 0.001 compared to the model group (unpaired t-test). The bars show min to max of data, and the small circles represent individual data points.