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. 2020 Oct 13;26(7):2964–2976. doi: 10.1038/s41380-020-00910-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Schematic presentation of the time course of transplantation and behavioral analysis. b–d The open field test indicated no difference in the time spent in the center, number of center crossings, or total distance traveled between organoid-injected mice and control mice injected with cerebrospinal fluid (control: n = 11 mice; transplantation: n = 12 mice). e The transplantation of cerebral organoids promoted the freezing response of the mice to a tone (control: n = 9 mice; transplantation: n = 13 mice). The data are shown as the mean ± SEM.