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. 2021 Jan 25;26(7):2685–2706. doi: 10.1038/s41380-020-00999-7

Table 1.

Characteristics and species-specific differences in common [219272] prion-like proteins.

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α-Syn alpha-synuclein, amyloid beta, AD Alzheimer’s disease, ALS Amyotrophic lateral sclerosis, AP amyloid plaques, APP amyloid precursor protein gene, CAA cerebral amyloid angiopathy, CBD corticobasal degeneration, CHR chromosome, CJD Creutzfeldt–Jakob’s disease, CP cored plaques, COP cored-only plaques, CTE chronic traumatic encephalopathy, DLB dementia with Lewy bodies, DN dystrophic neurites, DNP/CNP dense neuritic plaques/cored neuritic plaques, DP diffuse plaques, DS Down’s syndrome, FI fatal insomnia, FTLD frontotemporal lobar degeneration, FTDP-17 frontotemporal dementia with parkinsonism linked to chromosome 17, GFT glial fibrillary tangles, GGI globular glial inclusions, GI glial inclusions, GSS Gerstmann–Sträussler–Scheinker syndrome, HD Huntington’s disease, HpScl hippocampal sclerosis, HTT huntingtin protein, Htt huntingtin gene, MAPT microtubule-associated protein tau gene, mHTT mutant huntingtin, MSA multi-system atrophy, Namino-terminal inserts, NCI neural cytoplasmic inclusions, NFL neurofibrillary lesions, NFT neurofibrillary tangles, NII neuronal intranuclear inclusions, NP neuritic plaques, NT neuropil threads, PiD Pick’s disease, PD Parkinson’s disease, PDD Parkinson’s disease dementia, PHF paired helical filaments, PMA progressive muscular atrophy, PolyQ polyglutamine, PSP supranuclear palsy, PRNP gene encoding for PrP, PrP prion protein, PrP-CAA pure prion protein cerebral amyloid angiopathy, PrP-SA PrP‐systemic amyloidosis, SF straight filaments, SNCA gene encoding for α-Syn, SOD1 superoxide dismutase protein, SOD1 superoxide dismutase gene, S serine, SORT1 transmembrane receptor sortilin, T threonine, TARDP TDP-43 gene, TDP-43 TAR-binding domain protein-43, TsAs thorn-shaped astrocytes, VPSPr variably protease-sensitive prionopathy, Y tyrosine, 3R 3 repeats, 4R 4 repeats.