Table 1.
Demographics and clinical characteristics of 24 patients with Parkinson’s disease
| Patients N = 24 | LDR + N = 15 | LDR − N = 9 | p-value | |
|---|---|---|---|---|
| Sex, men (%) | 16 (66.6%) | 9 (60%) | 7 (77.7%) | 0.8 |
| Age (years) | 64.5 ± 6.9 | 62.7 ± 13.8 | 66.6 ± 4.2 | 0.3 |
| Age at onset (years) | 62.4 ± 7.5 | 63.2 ± 8.0 | 64.7 ± 4.8 | 0.3 |
| Disease duration (years) | 2.1 ± 1.1 | 2.2 ± 1.1 | 1.9 ± 1.3 | 0.5 |
| MAS, right (%) | 11 (45.8%) | 7 (46.7%) | 4 (44.4%) | 0.9 |
| UPDRS-ME score | 25.7 ± 9.1 | 24.0 ± 10.0 | 28.6 ± 6.8 | 0.2 |
| Hoehn and Yahr stage | 1.4 ± 0.5 | 1.3 ± 0.5 | 1.4 ± 0.5 | 0.7 |
| SDR^ | ||||
| MT basal, (msec) | 362 ± 81 | 370 ± 92 | 348 ± 62 | 0.3 |
| MT peak, (msec) | 309 ± 66 | 318 ± 73 | 294 ± 51 | 0.4 |
| Magnitude (%) | 19.6% | 18.9% | 20.8% | 0.5 |
| LDRa | ||||
| MT basal, at 15th day (msec) | 319 ± 70 | 308 ± 75 | 336 ± 58 | 0.4 |
| MT peak, at 15th day (msec) | 313 ± 72 | 307 ± 84 | 322 ± 48 | 0.7 |
| Magnitude (%) | 82.9% | 121.7% | 18.3% | 0.00001 |
Data are means ± standard deviations
MAS most affected side, UPDRS-ME unified Parkinson’s disease rating scale-motor examination, SDR short duration response, LDR long duration response, MT movement time, LDR + patients with LDR, LDR − patients without LDR
aValues recorded for the most affected side