Table 4.
Correlation between PD-L1-antibody, clone QR and the four budding/TIL groups
| PD-L1 IHC, clone QR | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Overall | TPS | IC | |||||||
| Budding/TIL groups | Positive (n/%) | Negative (n/%) | p value | Positive (n/%) | Negative (n/%) | p value | Positive (n/%) | Negative (n/%) | p value |
|
Low buds/high TILs (n = 129) |
76 (59.4) | 52 (40.6) | < 0.001 | 39 (30.2) | 90 (69.8) | < 0.001 | 74 (57.4) | 55 (42.6) | < 0.001 |
|
Low buds/low TILs (n = 128) |
50 (39.4) | 77 (60.6) | 10 (7.8) | 118 (92.2) | 48 (37.5) | 80 (62.5) | |||
|
High buds/high TILs (n = 42) |
24 (57.1) | 18 (42.9) | 7 (16.7) | 35 (83.3) | 23 (54.8) | 19 (45.2) | |||
| High buds/low TILs (n = 48) | 13 (27.1) | 35 (72.9) | 5 (10.4) | 43 (89.6) | 12 (25.0) | 36 (75.0) | |||
Statistically significant values are indicated in italics
IHC immunohistochemisty, TPS tumor positivity score, IC immune cell score, TILs tumor-infiltrating lymphocytes