Table 1.
Sociodemographic, tumor, and treatment characteristics of patients with right-sided and left-sided colon cancer (RCC, LCC) and rectal cancer (RC)
| RCC N = 1807 |
LCC N = 1972 |
RC N = 1633 |
||
|---|---|---|---|---|
| Gender | ||||
|
Male Female |
872 (48%) 935 (52%) |
1196(61%) 776 (39%) |
1070 (66%) 563 (34%) |
|
| Age | ||||
|
<65 years 65–74 years ≥75 years |
393 (22%) 731 (40%) 683 (38%) |
671 (34%) 829 (42%) 472 (24%) |
621 (38%) 641 (39%) 371 (23%) |
|
| Number of comorbidities | ||||
|
0 1 ≥2 Unknown |
783 (43%) 538 (30%) 300 (17%) 186 (10%) |
982 (50%) 524 (26%) 233 (12%) 233 (12%) |
844 (52%) 411 (25%) 190 (12%) 188 (11%) |
|
| ASA classification | ||||
|
ASA I ASA II ASA III ASA IV ASA unknown |
217 (12%) 937 (52%) 401 (22%) 26 (1%) 226 (13%) |
349 (18%) 969 (49%) 277 (14%) 16 (1%) 361 (18%) |
319 (20%) 881 (54%) 218 (13%) 6 (<1%) 209 (13%) |
|
| (y) pT stage | ||||
|
0 1 2 3 4 Unknown |
2 (<1%) 187 (11%) 306 (17%) 1049 (58%) 255 (14%) 8 (<1%) |
0 (0%) 552 (28%) 341 (17%) 855 (43%) 191 (10%) 33 (2%) |
119 (7%) 342 (21%) 506 (31%) 614 (38%) 38 (2%) 14 (1%) |
|
| (y) pN stage | ||||
|
0 1 2 Unknown |
1178 (65%) 401 (22%) 211 (12%) 17 (1%) |
,221 (62%) 414 (21%) 197 (10%) 140 (7%) |
1154 (71%) 303 (19%) 122 (7%) 54 (3%) |
|
| (y) pTNM stage | ||||
|
I II III |
441 (24%) 754 (42%) 612 (34%) |
813 (41%) 548 (28%) 611 (31%) |
845 (52%) 363 (22%) 425 (26%) |
|
| Morphology | ||||
|
Adenocarcinoma Mucinous adenocarcinoma Signet ring cell carcinoma |
1541 (85%) 242 (14%) 24 (1%) |
1857 (94%) 108 (6%) 7 (<1%) |
1549 (95%) 73 (4%) 11 (1%) |
|
| Differentiation grade | ||||
|
Well/moderate Poor/undifferentiated Unknown |
1370 (76%) 221 (12%) 216 (12%) |
1745 (88%) 90 (5%) 137 (7%) |
1337 (82%) 73 (4%) 223 (14%) |
|
| Microsatellite status | ||||
|
Stable Instable Unknown |
230 (13%) 102 (6%) 1475 (81%) |
315 (16%) 21 (1%) 1636 (83%) |
154 (9%) 8 (1%) 1471 (90%) |
|
| Treatment | ||||
| Neoadjuvant radiotherapy + surgical resection | 2 (<1%) | 332 (20%) | ||
| Neoadjuvant chemoradiation + surgical resection | 4 (<1%) | 519 (32%) | ||
| Surgery | 1345 (74%) | 1436 (73%) |
758 (46%) 24 (2%) |
|
| Surgical resection + adjuvant chemotherapy | 462 (26%) | 530 (27%) | ||
| Type of surgery | ||||
|
Surgical resection Endoscopic resection |
1299 (97%) 46 (3%) |
1165 (81%) 271 (19%) |
542 (72%) 216 (28%) |
|
| Residual tumor | ||||
|
No Yes Unknown |
1739 (96%) 29 (2%) 39 (2%) |
1863 (94%) 39 (2%) 70 (4%) |
1519 (93%) 66 (4%) 48 (3%) |
|
Left-sided included also rectosigmoidal tumors (N = 43). (y)pT0N0 was counted as stage I disease and (y)pT0N1-2 as stage III
Comparison of baseline characteristics statistically significant with chi-square tests (P < 0.0001)