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. 2021 Oct 11;11:20177. doi: 10.1038/s41598-021-99672-4

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© The Author(s) 2021, corrected publication 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of plasma cholesterol of controls and cows with focal, multifocal or diffuse lesiosn. Samples were selected from the case–control population and grouped according to the presence or absence of visible lesions in gut tissues. Cows with diffuse lesions (N = 26) were associated with decreased cholesterol plasma levels when compared with no visible lesions (N = 474) or with focal (N = 350) and multifocal (N = 32) lesions. The lines extending from the boxes indicate variability outside the upper and lower quartiles. The highest and lowest points are the maximum and the minimum of the data set, respectively. P values were calculated using an unpaired t-test. *P value < 0.001.