Table 3.
Quantitative trait loci (QTL) surpassing the significance threshold (P < 5 × 10−7) for evidence of an association with the diffuse lesions.
| BTA1 | QTL start (bp) | QTL end (bp) | P value most significant SNP | SNP position2 | Annotation | Genes in QTL3 | No of significant SNPs in QTL |
|---|---|---|---|---|---|---|---|
| 1 | 97006475 | 98111140 | 2.78E−07 | 97523460 | Intergenic | SLC7A14, CLDN11, SKIL, PRKCI, U2, PHC3, U6, GPR160, SEC62, SAMD7, LRRIQ4, LRRC34, MYNN, ACTRT3, Telomerase-vert, ENSBTAG00000049676, ENSBTAG00000042535, ENSBTAG00000045991, ENSBTAG00000053891, ENSBTAG00000047144 | 35 |
| 1 | 93955885 | 94925704 | 4.30E−07 | 94425704 | Intron | SPATA16, ECT2, NCEH1 | 8 |
| 3 | 63439078 | 64439078 | 3.16E−07 | 63939078 | Upstream | U6, ENSBTAG00000052602 | 1 |
| 7 | 15613384 | 17275615 | 2.91E−09 | 16113384 | Intron | PDE4A, KEAP1, s1PR5, ATG4D, KRI1, CDKN2D, AP1M2, SLC44A2, ILF3, QTRT1, DNM2, TMED1, C7H19orf38, CARM1, bta-mir3604-1, YIPF2, SMARCA4, TIMM29, TMED1, SPC24, KANK2,5S_rRNA, U6, LDLR, RAB3D, TMEM205, CCDC159, DOCK6, ANGPTL8, ELAVL3, ELOF1, PLPPR2, ACP5, EPOR, RGL3, ODAD3, PRKCSH, ZNF653, ECSIT, U4, INSR, ZNF557, ARHGEF18, CAMSAP3, PEX11G, RETN, XAB2, TEX45, MCEMP1, PET100, ZNF358, MCOLN1, PNPLA6, PCP2, STXBP2, TRAPPC5, FCER2, LRRC8B, CD209, MAP2K7, CLEC4G, EVI5L, CCL25, SNAPC2, TIMM44, bta-mir-2455, ELAVL1, FBN3, MARCHF2, CERS4, HNRNPM, ADAMTS10, bta-mir-339b, ANGPTL4, ACTL9, CD320, PRAM1, NDUFA7, ZNF414, RAB11B, OR2Z1, RPS28, MYO1F, SNORA70, ENSBTAG00000051140, ENSBTAG00000051490, ENSBTAG00000054591, ENSBTAG00000046336, ENSBTAG00000038680, ENSBTAG00000047612, ENSBTAG00000044018, ENSBTAG00000052882, ENSBTAG00000049668, ENSBTAG00000054873 | 21 |
| 7 | 26041927 | 27059884 | 1.12E−07 | 26547965 | Intergenic | CCDC192, 5S_rRNA, bta-mir-12007, CTXN3, PRRC1, MEGF10, U6, C7H5orf63, MARCHF3, ENSBTAG00000051246 | 12 |
| 7 | 23796173 | 25086968 | 1.73E−07 | 24296173 | Intergenic | CHSY3, MINAR2, ADAMTS19, ISOC1, SLC27A6, ENSBTAG00000051108, ENSBTAG00000051190 | 4 |
| 8 | 77894983 | 78394983 | 9.77E−09 | 78394983 | Intergenic | NTRK2 | 2 |
| 13 | 66829928 | 68799183 | 4.70E−10 | 67404014 | Intron | VSTM2L, TTI1, RPRD1B, TGM2, U6, LIAA1755, BPI, LBP, SNORA71, RALGAPB, ADIG, SLC32A1, ACTR5, PPP1R16B, FAM83D, DHX35, ENSBTAG00000051355, ENSBTAG00000047302, ENSBTAG00000050770, ENSBTAG00000052551, ENSBTAG00000044690 | 6 |
| 23 | 13569222 | 14569289 | 3.91091E−07 | 14069222 | Intergenic | KIF6, DAAM2, MOCS1, U6, LRFN2, ENSBTAG00000048842 | 3 |
1QTL location, 2SNP location in the genome assembly, 3Positional candidate genes are defined as genes that are located within 50 kb on either side of the identified QTL.