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ALT alleviated excess MMPs and ADAMTS5 expression in IL-1β-stimulated mouse chondrocytes. Chondrocytes were exposed to ALT (2.5, 5, and 10 μM) with or without IL-1β (10 ng/ml) for 24 h. (A) Western blot was employed to determine the expression of MMP1, MMP3, MMP13, and ADAMTS5. (B) Relative protein expression was qualified by ImageJ software, GAPDH was used as the internal control (n = 3). #p < 0.05 vs. control group; *p < 0.05 vs. IL-1β group; **p < 0.01 vs. IL-1β group.
