Table 2:

Random-effect Cox model with segmented linear splines for 1-year survival after lung transplantation (n = 9423).

	Hazards ratio (95% CI)	P value

Higher transplant volume (per case)^*
When <33 cases	0.989 (0.980 – 0.999)	0.036
When ≥33 cases	1.000 (0.996 – 1.003)	0.798
Higher recipient age (per year)	1.016 (1.008 – 1.023)	<0.001
Male recipient	1.105 (0.969 – 1.260)	0.137
Recipient ethnicity
White	Reference
Black	1.270 (1.040 – 1.552)	0.019
Others	1.020 (0.823 – 1.265)	0.856
Higher LAS (per unit)	1.006 (1.001 – 1.012)	0.027
Diagnosis grouping
Restrictive lung disease	Reference
Obstructive lung disease	1.013 (0.859 – 1.196)	0.876
Pulmonary vascular disease	1.424 (1.026 – 1.977)	0.035
Cystic fibrosis	0.996 (0.733 – 1.352)	0.978
Medical acuity
Not hospitalized	Reference
Hospitalized but not in ICU	0.958 (0.751 – 1.222)	0.732
In ICU	1.012 (0.754 – 1.359)	0.935
Higher mean pulmonary artery pressure (per mmHg)	1.006 (1.000 – 1.012)	0.052
Higher creatinine (per unit)	1.078 (0.989 – 1.174)	0.088
Preoperative ventilator support	1.469 (1.088 – 1.985)	0.012
Preoperative ECMO support	1.119 (0.812 – 1.542)	0.493
Longer ischemic time (per hour)	1.070 (1.033 – 1.108)	<0.001
Single lung transplant	1.067 (0.914 – 1.244)	0.413
Higher donor age (per year)	1.003 (0.999 – 1.008)	0.123
Donor non-heart beating	1.127 (0.819 – 1.551)	0.463
Higher donor PaO₂/FiO₂ (per 10 mmHg)	0.998 (0.993 – 1.003)	0.416

Two-segment linear splines.

Abbreviations: CI, confidence interval; ECMO, extracorporeal membrane oxygenation; ICU, intensive care unit; LAS, lung allocation score.