Table 3:
Baseline characteristics comparison between high-volume (≥33 cases/year) and low-volume (<33 cases/year) centers (n = 10007).
| Variables | Low-volume (n=3258) | High-volume (n=6749) | P value |
|---|---|---|---|
|
| |||
| Recipient age | 55.8 (±12.8) | 57.4 (±12.8) | <0.001 |
| Male recipient | 1946/3258 (59.7%) | 4041/6749 (59.9%) | 0.889 |
| Recipient ethnicity | <0.001 | ||
| White | 2642/3258 (81.1%) | 5485/6749 (81.3%) | |
| Black | 369/3258 (11.3%) | 548/6749 (8.1%) | |
| Others | 247/3258 (7.6%) | 716/6749 (10.6%) | |
| BMI | 25.6 (±4.6) | 25.5 (±4.4) | 0.205 |
| LAS | 46.9 (±17.2) | 49.1 (±18.7) | <0.001 |
| Diagnosis | <0.001 | ||
| Restrictive lung disease | 1749/3258 (53.7%) | 4003/6749 (59.3%) | |
| Obstructive lung disease | 979/3258 (30.0%) | 1826/6749 (27.1%) | |
| Pulmonary vascular disease | 110/3258 (3.4%) | 230/6749 (3.4%) | |
| Cystic fibrosis | 420/3258 (12.9%) | 690/6749 (10.2%) | |
| Medical acuity | 0.158 | ||
| Not hospitalized | 2567/3258 (78.8%) | 5230/6749 (77.5%) | |
| Hospitalized but not in ICU | 320/3258 (9.8%) | 859/6749 (9.8%) | |
| In ICU | 371/3258 (11.4%) | 660/6749 (12.7%) | |
| Mean pulmonary artery pressure | 27.6 (±10.5) | 27.4 (±10.9) | 0.505 |
| Creatinine | 0.9 (±0.6) | 0.8 (±0.3) | 0.002 |
| Preoperative ventilator support | 120/3258 (3.7%) | 440/6749 (6.5%) | <0.001 |
| Preoperative ECMO support | 128/3258 (3.9%) | 357/6749 (5.3%) | 0.003 |
| Ischemic time (hour) | 5.0 (±1.7) | 5.4 (±1.9) | <0.001 |
| Single lung transplant | 1002/3257 (30.8%) | 1892/6749 (28.0%) | 0.005 |
| Donor age | 33.8 (±13.4) | 35.7 (±14.2) | <0.001 |
| Donor non-heart beating | 63/3258 (1.9%) | 253/6749 (3.7%) | <0.001 |
| Donor PaO2/FiO2 | 432 (368–492) | 438 (374–497) | 0.007 |
Abbreviations: CI, confidence interval; ECMO, extracorporeal membrane oxygenation; ICU, intensive care unit; LAS, lung allocation score.