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. 2021 Oct 11;11:20119. doi: 10.1038/s41598-021-99471-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Mixing of an aqueous solution of Rhodamine B-dextran 70 kDa with distilled water. (a) fluorescence image of design A, performed with the same parameters as in Fig. 4, (b) the experimental Dextran-Rhodamine B conjugate concentration profiles across the channel at the indicated location in (a) (dash line) compared to the COMSOL simulation results at the same location. The same experimental concentration profiles and simulation results for pattern C were plotted accordingly in (c).