Table 1.
Demographics and history.
| Demographics and history | Group 1 | Group 2 | Group 3 | p | |
|---|---|---|---|---|---|
| Age | Median (range) | 54 (23–92) | 51.5 (28–82) | 51 (24–84) | 0.086 |
| BMI | |||||
| Underweight | n (%) | 5 (0.8) | 1 (2.3) | 3 (2.9) | 0.476 |
| Normal | 155 (25.3) | 10 (22.7) | 23 (22.3) | ||
| Overweight | 226 (36.9) | 17 (38.6) | 44 (42.7) | ||
| Obese | 227 (37.0) | 16 (36.4) | 33 (32.0) | ||
| BMI | Median (range) | 28.3 | 27.8 | 27.8 | 0.737 |
| (14.9–51.3) | (18.3–44.3) | (16.5–48.3) | |||
| Smoking | |||||
| No | n (%) | 471 (65.1) | 38 (76.0) | 82 (66.1) | 0.287 |
| Yes | 253 (34.9) | 12 (24.0) | 42 (33.9) | ||
| Hormone use | |||||
| No | n % | 407 (52.9) | 30 (60.0) | 80 (63.5) | 0.064 |
| OC or HRT | 164 (21.3) | 15 (30.0) | 24 (19.0) | ||
| OC | 145 (18.9) | 4 (8.0) | 17 (13.5) | ||
| HRT | 31 (4.0) | 0 (0) | 5 (4.0) | ||
| OC + HRT | 22 (2.9) | 1 (2.0) | 0 (0) | ||
| Diabetes | |||||
| No | n % | 684 (84.4) | 51 (89.5) | 116 (86.6) | 0.509 |
| Yes | 126 (15.6) | 6 (10.5) | 18 (13.4) | ||
| Comorbid disease | |||||
| No | n % | 221 (47.5) | 15 (60.0) | 30 (48.4) | 0.477 |
| Yes | 244 (52.5) | 10 (40.0) | 32 (51.6) | ||
| Family history | |||||
| No | n % | 607 (77.1) | 45 (83.3) | 98 (76.0) | 0.531 |
| Yes | 180 (22.9) | 9 (16.7) | 31 (24.0) | ||
| Menopausal status | |||||
| Premenopausal | n % | 329 (36.3) | 27 (40.3) | 72 (41.4) | 0.161 |
| Postmenopausal | 573 (63.3) | 40 (59.7) | 99 (56.9) | ||
| Male | 3 (0.4) | 0 (0) | 3 (1.7) | ||
| CEA | Median (range) | 1.7 | 2 | 2.2 | < 0.001 |
| (0.2–56.2) | (0.4–26.1) | (0.2–312.1) | |||
| CA15-3 | Median (range) | 15.1 | 18.2 | 20.1 | < 0.001 |
| (0.5–333.7) | (4–127.1) | (5.8–698.5) | |||
BMI body mass index, OC oral contraceptives, HRT hormone replacement therapy.