Skip to main content
. 2021 Oct 11;11:20175. doi: 10.1038/s41598-021-99726-7

Table 3.

Adjuvant and neoadjuvant treatment of the groups.

Systemic therapies Group 1 Group 2 Group 3 p
Neoadjuvant treatment (NAT)
No n (%) 822 (88.6) 61 (89.7) 147 (79.5) 0.003
Yes 106 (11.4) 7 (10.3) 38 (20.5)
Response to NAT
No n (%) 8 (8.8) 4 (66.7) 6 (17.6) NA
Partial 54 (59.3) 2 (33.3) 27 (79.4)
Almost complete 14 (15.4) 0 (0) 1 (2.9)
Complete 15 (16.5) 0 (0) 0 (0)
Adjuvant CT
No n (%) 225 (29.6) 16 (27.6) 61 (38.9) NA
Taxane and/or AC 517 (67.9) 41 (70.7) 92 (58.6)
CMF 8 (1.1) 0 (0) 1 (0.6)
Other 11 (1.4) 1 (1.7) 3 (1.9)
GCSF use
No n (%) 285 (62.9) 29 (70.7) 54 (62.1) 0.588
Yes 168 (37.1) 12 (29.3) 33 (37.9)
Radiotherapy
No n (%) 193 (22.6) 16 (26.7) 43 (30.9) 0.088
Yes 662 (77.4) 44 (73.3) 96 (69.1)
Hormonotherapy
No n (%) 175 (20.2) 21 (31.8) 72 (44.2) < 0.001
Tmx 248 (28.7) 17 (25.8) 45 (27.6)
Aromatase Inh 398 (46.0) 25 (37.9) 40 (24.5)
Switch 44 (5.1) 3 (4.5) 6 (3.7)

NA not available, CT chemotherapy.