Table 2.
Vitreous levels of the angiogenesis and inflammation mediators.
| Mediators | PDR (n = 38) | Non-DM (n = 37) | p-value |
|---|---|---|---|
| Syndecan-1 (pg/ml) | 196.75 (106.86, 446.55) | 108.26 (68.78,171.45) | 0.004* |
| CSF-1R (pg/ml) | 24352.98 (13319.23, 58648.69) | 39665.10 (13459.57, 51903.36) | 0.695 |
| PIGF (pg/ml) | 35.60 (3.49, 283.08) | 0.81 (0.37, 1.29) | <0.001* |
| ANGPTL-4 (pg/ml) | 112378.13 (31458.05, 387799.98) | 26890.31 (8022.31, 54353.15) | <0.001* |
| VEGF (pg/ml) | 22.14 (5.40, 204.52) | 3.15 (2.38, 4.15) | 0.001* |
| IL-6 (pg/ml) | 45.32 (11.31, 360.45) | 31.84 (13.12, 207.56) | 0.719 |
| IL-8 (pg/ml) | 50.71 (19.84, 256.68) | 23.69 (10.70, 49.14) | 0.038* |
| MCP-1 (pg/ml) | 1107.18 (610.26, 2084.73) | 1315.25 (590.25, 2400.45) | 0.611 |
| TNF-α (pg/ml) | 8.81 (6.68, 46.28) | 7.92 (6.79, 9.83) | 0.354 |
| ICAM-1 (pg/ml) | 1209.64 (318.50, 2075.00) | 572.37 (224.68, 1215.11) | 0.080 |
PDR, proliferative diabetic retinopathy; DM, diabetes mellitus.
*
Statistically significant (p value < 0.05).