Table 4.
Correlations between vitreous levels of the angiogenesis and inflammation mediators and systemic factors.
| Systemic factors | FBG, mmol/l | HbA1c, % | sCr, μmol/l | BUN, mmol/l | eGFR, ml/min/1.73 m2 |
|---|---|---|---|---|---|
| r value | r value | r value | r value | r value | |
| (p-value) | (p-value) | (p-value) | (p-value) | (p-value) | |
| Syndecan-1 (pg/ml) | −0.325 (0.047*) |
−0.054 (0.746) |
0.572 (<0.001*) |
0.629 (<0.001*) |
−0.603 (<0.001*) |
| PIGF (pg/ml) | −0.350 (0.031*) |
−0.231 (0.163) |
0.338 (0.038*) |
0.447 (0.005*) |
−0.356 (0.028*) |
| ANGPTL4 (pg/ml) | −0.362 (0.026*) |
−0.279 (0.101) |
0.428 (0.007*) |
0.638 (<0.001*) |
−0.453 (0.004*) |
| VEGF (pg/ml) | −0.168 (0.315) |
−0.268 (0.104) |
0.000 (0.998) |
0.184 (0.270) |
−0.019 (0.910) |
| IL-8 (pg/ml) | −0.403 (0.012*) |
−0.226 (0.173) |
0.328 (0.044*) |
0.509 (0.001*) |
−0.365 (0.024*) |
FBG, fasting blood glucose; HbA1c, glycated hemoglobin; sCr, serum creatinine; BUN, blood urea nitrogen; eGFR, estimated glomerular filtration rate.
*
Statistically significant (p value < 0.05).