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. 2021 Sep 28;12:732716. doi: 10.3389/fphar.2021.732716

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Copyright © 2021 Pan, Han, Xu, Peng, Bai, Zhou and He.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Volcano plot analysis of differential metabolites in A549 cells after exposure to 80 μM EGCG. The x-axis represents log₂ (fold change), while the y-axis represents p-value in -log₁₀ scale. The significantly up-regulated metabolites were indicated in red squares and down-regulated in green triangles. (p < 0.05 and fold change >1.5 or <0.75).