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. 2021 Sep 28;12:732716. doi: 10.3389/fphar.2021.732716

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Copyright © 2021 Pan, Han, Xu, Peng, Bai, Zhou and He.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pathway analysis overview depicting altered metabolic pathways in A549 cells from control and 80 μM EGCG-treated groups. The metabolic pathways are displayed as distinctly colored circles depending on their enrichment analysis scores (vertical axis, shade of red) and topology (pathway impact, horizontal axis, circle diameter) via MetaboAnalyst 5.0. (A): Glycine, serine and threonine metabolism, (B): Alanine, aspartate and glutamate metabolism, (C): Aminoacyl-tRNA biosynthesis, (D): Glyoxylate and dicarboxylate metabolism E: Arginine and proline metabolism.