Table 2.
The association between GRB10 rs1800504 genetic variation and the risk of vascular complications in T2DM patients.
| Events | Genotype | Number of patients (%) | OR (95%CI) | p-value |
|---|---|---|---|---|
| Coronary heart disease* | TT | 26 (16.3) | Ref. | / |
| CT | 146 (30.6) | 2.35 (1.40–3.95) | 0.001 | |
| CC | 76 (25.9) | 2.07 (1.18–3.61) | 0.011 | |
| Peripheral neuropathy | TT | 101 (63.5) | Ref. | / |
| CT | 296 (64.5) | 1.09 (0.73–1.63) | 0.67 | |
| CC | 189 (64.5) | 1.20 (0.78–1.84) | 0.41 | |
| Retinopathy | TT | 15 (9.4) | Ref. | / |
| CT | 56 (11.7) | 1.06 (0.71–1.57) | 0.79 | |
| CC | 37 (12.6) | 1.20 (0.79–1.83) | 0.40 | |
| Nephropathy | TT | 66 (41.3) | Ref. | / |
| CT | 282 (47.3) | 0.93 (0.62–1.39) | 0.72 | |
| CC | 122 (41.9) | 1.08 (0.70–1.67) | 0.73 | |
| 33 (11.3) | ||||
| Cerebral infarction | TT | 17 (10.6) | Ref. | / |
| CT | 62 (13.0) | 1.04 (0.57–1.91) | 0.90 | |
| CC | 33 (11.3) | 1.03 (0.53–2.00) | 0.92 | |
| Diabetic foot | TT | 24 (15.0) | Ref. | / |
| CT | 79 (16.6) | 1.06 (0.63–1.80) | 0.82 | |
| CC | 49 (16.7) | 1.22 (0.70–2.13) | 0.49 |
*
p < 0.05, indicates a significant statistical difference. The bold values mean p value is less than 0.05.