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. 2021 Oct;129:112375. doi: 10.1016/j.msec.2021.112375

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© 2021 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 8 — DIP release expressed in μg as a function of time for the different DIP loaded grafts (A). DIP release expressed in percentage as a function of initial DIP drug loading (B) (n = 4). Microscopy image of the cross-section of a core shell implant prepared with 20% DIP in the core and PCL 25 kDa in the shell (C). The graph was printed using 2 extruders from the BioScaffolder equipment: 20% DIP core was printed with a mechanical extruder (nozzle size: 0.50 mm) and the PCL shell printed with pneumatic extruder (nozzle size: 0.25 mm). Bottom panel: fluorescence microscopy image.