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. 2021 Sep 28;8:753295. doi: 10.3389/fmed.2021.753295

Table 4.

Logistic regression to determine the odds of activities of daily living (ADL) disability at 1-year follow-up.

ORs for the incidence of ADL disability (95% CI)
Unadjusted p Model 1 p Model 2 p Model 3 p
Age group
65–74 y Ref Ref Ref Ref
75–84 y 2.72 (2.30, 3.23) 0.956 2.58 (2.16, 3.08) 0.870 2.64 (2.22, 3.16) 0.631 2.52 (2.11, 3.02) 0.678
≥85 y 7.50 (5.03, 11.14) <0.001 6.92 (4.56, 10.45) <0.001 7.84 (5.18, 11.79) <0.001 7.05 (4.64, 10.65) <0.001
Sex
Male Ref Ref Ref Ref
Female 1.45 (1.22, 1.72) <0.001 1.49 (1.24, 1.80) <0.001 1.54 (1.28, 1.86) <0.001 1.49 (1.23, 1.80) <0.001
Education
High school or above Ref Ref Ref Ref
Middle school or below 1.63 (1.39, 1.92) <0.001 1.17 (0.98, 1.39) 0.091 1.14 (0.94, 1.39) 0.009 1.18 (0.99, 1.41) 0.066
Married
Yes Ref Ref Ref Ref
No 1.60 (1.33, 1.92) <0.001 1.09 (0.89, 1.33) 0.391 1.26 (1.06, 1.50) 0.182 1.10 (0.90, 1.34) 0.337
No. of chronic diseases a
0 Ref / Ref /
1 1.12 (0.91, 1.39) 0.028 / 1.08 (0.87, 1.35) 0.063 1.07 (0.86, 1.33) 0.097
2 1.35 (1.71, 1.69) <0.001 / 1.21 (0.96, 1.53) 0.086 1.17 (0.93, 1.48) 0.794
≥3 1.86 (1.41, 2.44) <0.001 / 1.73 (1.30, 2.30) <0.001 1.64 (1.23, 2.18) 0.001
No. of impairments in IC domains b
0 Ref Ref / Ref
1 1.18 (0.96, 1.44) 0.002 1.07 (0.88, 1.32) 0.014 / 1.07 (0.87, 1.31) 0.0195
2 1.79 (1.44, 2.24) <0.001 1.43 (1.14, 1.80) <0.001 / 1.40 (1.11, 1.76) <0.001
≥3 3.41 (2.58, 4.50) <0.001 2.32 (1.72, 3.11) <0.001 / 2.23 (1.66, 2.99) <0.001
AUC 0.549a/0.589b 0.685 0.681 0.691

ADL, activities of daily living; OR, odds ratio; No., number; ref, reference; IC, intrinsic capacity; AUC, area under the curve.

a

Multimorbidity status: Chronic diseases include: hypertension, coronary artery disease, diabetes mellitus, stroke, tumor, and chronic obstructive pulmonary.

b

Intrinsic capacity status: IC includes five domains: locomotion, vitality, sensory, cognition, and psychological.

Model 1: Adjustment for age, sex, education, and marriage to determine the odds of disability based on IC impairment.

Model 2: Adjustment for age, sex, education, and marriage to determine the odds of disability based on multimorbidity status.

Model 3: Adjustment for multimorbidity status, age, sex, education, and marriage to determine the odds of disability based on IC impairment.