Figure 1.

The genetic features of 23 m⁶A regulators in early-stage lung adenocarcinoma of the TCGA cohort. (A) The genetic mutations of 23 m⁶A regulators in 92 patients. (B) The correlation analysis between DNA methylation and 23 m⁶A regulators’ expression (*P < 0.05; **P < 0.01; ***P < 0.001). (C) The CNA landscape of 23 m⁶A regulators. Gain represents gain and high level amplification, loss represents homozygous deletion and hemizygous deletion. (D) The correlation analysis between the 23 m⁶A regulators via the Spearman correlation method. (E) The m⁶A regulators expression between normal and tumor groups (*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001). ns, not significant.