FIGURE 2.

Loss of global NPRC decreases white adipose mass and white adipocyte size. (A) Expression of NPRC in subdermal adipose tissue from ApoE^−/−NPRC^−/− mice and ApoE^−/− mice measured by Western blot. (B) Quantification of Expression of NPRC in subdermal adipose tissue from ApoE^−/−NPRC^−/− mice and ApoE^−/− mice (n = 5). (C) The representative images of immunohistochemical staining for NPRC in subdermal adipose tissue in APOE^−/−NPRC^−/− mice and APOE^−/− mice. (D) Quantification of ratio of NPRC positive area in adipose tissue (n = 5). (E) The representative images of adipose tissue mass of APOE^−/−NPRC^−/− mice and APOE^−/− mice. (F) Quantification of adipose tissue mass of APOE^−/−NPRC^−/− mice and APOE^−/− mice (n = 5). (G) The representative images of haematoxylin and eosin staining in subdermal white adipose tissue in APOE^−/−NPRC^−/− mice and APOE^−/− mice. (H) Quantification of average adipocyte size in subdermal white adipose tissue (n = 5)