TABLE 1.
Single fiber characteristics for DIAm Force Model.
Fiber type | Fatigue index | Contribution to total DIAm volume (%) 6-month | Maximum specific force (N/cm2) 6-month | Residual specific force (N/cm2) 6-month | Contribution to total DIAm volume (%) 24-month | Maximum specific force (N/cm2) 24-month | Residual specific force (N/cm2) 24-month |
Type I | 0.8a | 14 | 20b | 16d | 28 | 20 | 16d |
Type IIa | 0.8a | 14 | 24b | 19d | 21 | 24 | 19d |
Type IIx/IIb | 0.1a | 72 | 33b | 3d | 51 | 23c | 2d |
aFatigue index based on past reports for DIAm motor units (Fournier and Sieck, 1988).
bSpecific force data from DIAm single fibers was published previously (Geiger et al., 2000, 2001a, 2002).
cDerived from observed reductions in total MyHC expression, and attributed to the vulnerable type IIx/IIb fibers (Elliott et al., 2016).
dResidual specific forces following fatigue calculated from values derived from a, b, and c.