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. 2021 Sep 28;8:695375. doi: 10.3389/fvets.2021.695375

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Copyright © 2021 Di Cerbo, Roncati, Marini, Carnevale, Zavatti, Avallone and Corsi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Histopathology of the liver samples stained with HE from rats treated with D-galactosamine and D-galactosamine + DHEA for 48 h. (A) Normal control group with proper architecture of the liver, (B) D-galactosamine-induced hepatotoxicity characterized by marked steatosis and hepatocyte degeneration, and (C) D-galactosamine + DHEA with steatosis and altered parenchymal structure.