Table 3.
Beta estimates and confidence intervals for the association between FTO rs9939609 polymorphism and CRC.
| Model | Components | Chi-square | df | B | P-value |
|---|---|---|---|---|---|
| Model 1 | 21.46 | 3 | 0.000 | ||
| Genotype (TT) | 0.111 | ||||
| Genotype (TA) | −1.325 | 0.111 | |||
| Genotype (AA) | −1.666 | 0.042 | |||
| Age | 0.042 | 0.000 | |||
| Model 2 | 22.89 | 5 | 0.000 | ||
| Genotype (TT) | 0.118 | ||||
| Genotype (TA) | −1.380 | 0.099 | |||
| Genotype (AA) | −1.672 | 0.042 | |||
| Gender | −0.438 | 0.231 | |||
| Age | 0.041 | 0.001 | |||
| Model 3 | 25.26 | 10 | 0.005 | ||
| Genotype (TT) | 0.124 | ||||
| Genotype (TA) | −1.424 | 0.090 | |||
| Genotype (AA) | −1.676 | 0.043 | |||
| Gender | −0.542 | 0.154 | |||
| Marital (Unmarried) | 0.327 | ||||
| Marital (Married) | −1.190 | 0.422 | |||
| Marital (Unknown) | −0.213 | 0.869 | |||
| Age | 0.029 | 0.039 | |||
| Model 4 | 29.00 | 11 | 0.002 | ||
| Genotype (TT) | 0.170 | ||||
| Genotype (TA) | −1.269 | 0.143 | |||
| Genotype (AA) | −1.570 | 0.067 | |||
| Gender (Male) | −0.506 | 0.191 | |||
| Ethnicity (Fars) | 0.852 | ||||
| Ethnicity (Turk) | −21.295 | 1.000 | |||
| Ethnicity (Lor) | −20.911 | 1.000 | |||
| Ethnicity (Kurd) | −21.117 | 1.000 | |||
| Ethnicity (Arab) | −19.685 | 1.000 | |||
| Ethnicity (Others) | −2.263 | 1.000 | |||
| Marital (Unmarried) | 0.313 | ||||
| Marital (Married) | −1.277 | 0.396 | |||
| Marital (Unknown) | −0.265 | 0.840 | |||
| Age | 0.030 | 0.038 | |||