MEDLINE – SEARCH

	Concept 1	Search #	Concept 2	Search #	Concept 3	Search #	Concept 4
#1	migraine[Text Word]	#11	preventive therapy[Text Word]	#40	beta-blocker[Text Word]	#85	randomized controlled trial[Text Word]
#2	episodic migraine[Text Word]	#12	prophylaxis[Text Word]	#41	topiramate[Text Word]	#86	controlled clinical trial[Text Word]
#3	chronic migraine[Text Word]	#13	treatment[Text Word]	#42	anticonvu*[Text Word]	#87	randomized controlled*[Text Word]
#4	migraine with aura[Text Word]	#14	therapies[Title/Abstract]	#43	antiepilep*[Text Word]	#88	random allocation[Title/Abstract]
#5	migraine without aura[Text Word]	#15	prevention[Text Word]	#44	topira*[Text Word]	#89	Double-Blind Method[MeSH Terms]
#6	migrain*[Text Word]	#16	prophylactic[Text Word]	#45	valproate[Text Word]	#90	Single-Blind Method[MeSH Terms]
#7	cephalgi*[Text Word]	#17	preventive treatment[Text Word]	#46	valpro*[Text Word]	#91	clinical trial[Text Word]
#8	migraine*[Text Word]	#18	pharmacologic[Title/Abstract]	#47	candesartan[Text Word]	#92	clinical trials[Text Word]
#9	cephalalgi*[Text Word]	#19	prevent*[Text Word]	#48	candesart*[Text Word]	#93	Prospective Studies[MeSH Terms]
#10	Migraine Disorders [Mesh Terms]	#20	drug*[Text Word]	#49	onabotulinum[Text Word]	#94	control*[Text Word]
		#21	preventative*[Title/Abstract]	#50	botox[Text Word]	#95	prospectiv*[Text Word]
		#22	therapy[Title/Abstract]	#51	onabotulinum*[Text Word]	#96	Placebos[MeSH Terms]
		#23	effective[Title/Abstract]	#52	erenumab[Text Word]	#97	placebo*[Text Word]
		#24	frequency*[Title/Abstract]	#53	CGRP[Text Word]	#98	random*[Text Word]
		#25	reduction[Title/Abstract]	#54	anti-CGRP[Text Word]	#99	blind*[Text Word]
		#26	reduces[Title/Abstract]	#55	Calcitonin Gene-Related*[Text Word]	#100	Evaluation Studies as Topic[MeSH Terms]
		#27	reduced[Title/Abstract]	#56	gepants[Text Word]	#101	Comparative Study[Publication Type]
		#28	attack*[Title/Abstract]	#57	*gepant[Text Word]	#102	trial*[Text Word]
		#29	month*[Text Word]	#58	Valproic Acid[MeSH Terms]	#103	controll*[Text Word]
		#30	therapeutic[Title/Abstract]	#59	Botulinum Toxins, Type A[MeSH Terms]	#104	efficacy*[Text Word]
		#31	effectively[Title/Abstract]	#60	Amitriptyline[MeSH Terms]	#105	compare*[Text Word]
		#32	effect[Title/Abstract]	#61	fremanezumab[Supplementary Concept]	#106	Clinical Trials as Topic[MeSH Terms]
		#33	Prevention and Control[MeSH Terms]	#62	TEV-48125[Text Word]	#107	*blind*[Text Word]
		#34	Drug Therapy[MeSH Terms]	#63	galcanezumab[Supplementary Concept]	#108	Multicenter Study[Publication Type]
		#35	Treatment Outcome [MeSH Terms]	#64	eptinezumab[Supplementary Concept]	#109	Clinical Studies as Topic[MeSH Terms]
		#36	Therapeutic Use [MeSH Subheading]	#65	telcagepant[Supplementary Concept]	#110	Cross-Over Studies[MeSH Terms]
		#37	monthly[Text Word]	#66	Propranolol[MeSH Terms]	#111	Clinical Trial[Publication Type]
		#38	outcome*[Text Word]	#67	Metoprolol[MeSH Terms]	#112	Drug Evaluation[MeSH Terms]
		#39	preventative treatment[Text Word]	#68	Nebivolol[MeSH Terms]	#113	Preliminary Data[MeSH Terms]
				#69	Adrenergic Beta-Antagonists[MeSH Terms]	#114	pivot*[Text Word]
				#70	Bisoprolol[MeSH Terms]	#115	Review Literature as Topic[MeSH Terms]
				#71	Flunarizine[MeSH Terms]	#116	Systematic Review[Publication Type]
				#72	Verapamil[MeSH Terms]	#117	Review[Publication Type]
				#73	Anticonvulsants[MeSH Terms]
				#74	Calcitonin Gene-Related Peptide[MeSH Terms]
				#75	Receptors, Calcitonin Gene-Related Peptide[MeSH Terms]
				#76	atogepant[Text Word]
				#77	rimegepant[Text Word]
				#78	Pituitary Adenylate Cyclase-Activating Polypeptide[MeSH Terms]
				#79	PACAP*[Text Word]
				#80	AMG334[Text Word]
				#81	PAC1[Text Word]
				#82	filorexant[Text Word]
				#83	orexin[Text Word]
				#84	LBR-101[Text Word]