TABLE 5.

Frequency of FoxP3 in CD4⁺CD25⁺ cells in patients with acute AOSD, remission AOSD and healthy controls

		Acute AOSD	Remission AOSD	HC	p value
		(n = 27)	(n = 11)	(n = 16)	*/**
In total lymphocytes
	% CD4+CD25+ cells	45.75 ± 15.48	43.40 ± 10.89	40.14 ± 18.02	0.374/0.218
In CD4+CD25+ cells
	% FoxP3	8.43 ± 7.83	18.73 ± 8.48	25.24 ± 9.62	0.013/<0.0001

Data are presented as the mean ± standard deviation (SD).

Abbreviations: HC, healthy controls; FoxP3, forkhead box protein 3.

^*Comparisons between acute and remission phases in 11 acute adult‐onset Still’s disease (AOSD) patients by using Wilcoxon’s signed‐rank test.

^**Comparisons between 27 acute AOSD patients and 16 HC using the Mann–Whitney U‐test. A p value less than 0.05 was considered statistically significant.