Figure 3.

Magnetic Resonance Imaging of the brain of case #4 pre- and post-cystic drainage, and before and after treatment with BRAF/MEK inhibitors. On 01/2016, MRI brain performed pre- (A. and E.) and post-surgical drainage of the cystic component of the lesion and before starting treatment with maintenance temozolomide (B. and F.). On 02/2016, MRI with rapid refilling of the cystic component of the lesion and before starting treatment with BRAF/MEK inhibitors (C. and G.). Most current MRIs as of 10/2020 show stable disease since started on BRAF/MEK inhibitors, without requiring further surgical drainage (D. and H.). A–D = T1 Post-Gadolinium. E–H = T2 FLAIR sequences.