Table 2.
Comparison of good responders and poor responders, in terms of change in mean PE (E1%), post each cycle of NACT compared with baseline (pre-NACT)
Time point comparison | Change in PE (E1%) from pre-NACT to third cycle of NACT | Comparison of the two groups in terms of difference of PE (E1%) from pre-NACT to follow-up NACT cycles | ||||
---|---|---|---|---|---|---|
Good responder | Poor responder | |||||
Mean (SD) of absolute change | Mean (SD) of % change | Mean (SD) of absolute change | Mean (SD) of % change | p-value of absolute change | p-value of % change | |
Post first cycle - Pre-NACT | −0.71 (1.03) | −8.0% (19.5) | 0.65 (1.07) | 18.5% (31.2) | <0.001 | <0.001 |
Post second cycle - Pre-NACT | −1.52 (1.34) | −19.8% (21.7) | 1.06 (1.36) | 30.1% (38.7) | <0.001 | <0.001 |
Post third cycle - Pre-NACT | −2.03 (1.24) | −28.5% (20.4) | 0.98 (1.84) | 29.2% (49.1) | <0.001 | <0.001 |
NACT, neoadjuvant chemotherapy; PE, peak enhancement; SD, standard deviation.