Table 3.

Comparison of good responders and poor responders, in terms of change in mean TTP (E1s), post each cycle of NACT compared with baseline (pre-NACT)

Time point comparison	Change in TTP (E1s) from pre-NACT to third cycle of NACT				Comparison of the two groups in terms of difference of TTP (E1s) from pre-NACT to follow-up NACT cycles
	Good responder		Poor responder
	Mean (SD) of absolute change	Mean (SD) of % change	Mean (SD) of absolute change	Mean (SD) of % change	p-value of absolute change	p-value of % change
Post first cycle - pre-NACT	0.75 (1.02)	38.4% (55.5)	−0.16 (3.36)	7.6% (55.9)	0.054	0.031
Post second cycle - pre-NACT	1.72 (1.90)	83.6% (89.4)	0.14 (4.11)	22.3% (100.1)	0.014	0.013
Post third cycle - pre-NACT	5.19 (4.04)	205.0% (151.2)	0.26 (6.09)	38.1% (153.8)	0.008	0.004

NACT, neoadjuvant chemotherapy; SD, standard deviation; TTP, time-to-peak.