Table 5.

Comparison of good responders and poor responders, in terms of change in mean MTT (E1s), post each cycle of NACT compared with baseline (pre-NACT)

Time point comparison	Change in MTT (E1s) from pre-NACT to third cycle of NACT				Comparison of the two groups in terms of difference of MTT (E1s) from pre-NACT to follow-up NACT cycles
	Good responder		Poor responder
	Mean (SD) of absolute change	Mean (SD) of % change	Mean (SD) of absolute change	Mean (SD) of % change	p-value of absolute change	p-value of % change
Post first cycle - pre-NACT	0.75 (0.95)	24.1% (26.9)	−3.44 (3.59)	−25.8% (36.7)	<0.001	0.001
Post second cycle - pre-NACT	5.35 (3.96)	148.0% (139.9)	−3.26 (6.50)	3.2% (130.4)	<0.001	<0.001
Post third cycle - pre-NACT	8.08 (4.91)	209.8% (133.6)	−1.96 (7.99)	12.5% (130.0)	0.001	<0.001

MTT, mean transit time; NACT, neoadjuvant chemotherapy; SD, standard deviation.