Figure 2. Network Structures of the Outcomes.

A, Primary outcome: pain freedom at 2 hours. B, Secondary outcome: pain relief at 2 hours. C, Secondary outcome: any adverse event. The lines between nodes represent direct comparisons in various trials, and the size of each circle is proportional to the size of the population involved in each specific treatment. The thickness of the lines is proportional to the number of trials connected to the network. One study was excluded from our analysis because it compared subcutaneous dihydroergotamine and subcutaneous sumatriptan and did not connect with the other studies in the network.