Table 2.
Comparison of clinical parameters between two groups
| Parameter | Midazolam group (n=40) | Control group (n=40) | P |
|---|---|---|---|
| Duration of intubation (mean±SD) | 23.5±6.7 | 18.8±4.8 | 0.001 |
| SpO2<70% during intubation (%) | 55 | 5 | 0.0001 |
| Duration of intubation of>30 s (%) | 34.2 | 2.5 | 0.0001 |
| Mouth and laryngeal bleeding (%) | 37.5 | 2.5 | 0.0001 |
| Awake and resisting patients (%) | 80 | 5 | 0.0001 |
| Successful intubation | |||
| At first trying (%) | 66.7 | 92.5 | 0.004 |
| At second trying (%) | 33.3 | 7.5 | |
| Intubation condition (%) | |||
| Excellent | 0 | 82.5 | 0.0001 |
| Good | 0 | 10 | |
| Acceptable | 30 | 2.5 | |
| Weak | 70 | 5 | |
| Neonatal condition 10 min after INSURE (%) | |||
| Excellent | 0 | 82.5 | 0.0001 |
| Good | 0 | 15 | |
| Acceptable | 30 | 2.5 | |
| Weak | 70 | 0 | |
| Blood pressure (mm Hg) (±SD) | |||
| Before intubation | 45.6±9.5 | 43.2±6.3 | 0.19 |
| After intubation | 46.7±9.6 | 43.8±6.3 | 0.12 |
| 10 min after INSURE | 45.6±9.9 | 44.6±6 | 0.15 |
| SpO2 before intubation (%) (±SD) | 83.3±13.1 | 92.3±4.3 | 0.0001 |
| SPO2 after intubation (%) (±SD) | 88.05±13.7 | 95.1±1.8 | 0.002 |
| SpO2 10 min after INSURE (%) (±SD) | 94.4±2.1 | 95.2±1.8 | 0.03 |
| Heart rate before intubation (beat/minute) (±SD) | 143.08±12.7 | 146.9±15.1 | 0.41 |
| Heart rate after intubation (beat/minute) (±SD) | 143.9±12.6 | 146.5±14.7 | 0.21 |
| Heart rate 10 min after INSURE intubation (beat/minute) (±SD) | 143±22.5 | 147±13.4 | 0.11 |
SD=Standard deviation