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. 2021 Oct 12;95(5):336–344. doi: 10.1016/j.anpede.2020.10.007

Table 2.

Diagnostic tests and treatments used.

Total Confirmed COVID-19 Unconfirmed COVID-19 P
Patients, n (%) 72 (100%) 40 (55.5%) 32 (44.5%)
Chest X-ray, n (%)
 Normal
 Interstitial infiltrates 19 (26.4%) 10 (25%) 9 (28.1%) a
 Unilateral pneumonia 28 (38.9%) 15 (37.5%) 13 (40.6%)
 Bilateral pneumonia 10 (13.9%) 6 (15%) 4 (12.5%)
 Not performed 6 (8.3%) 2 (5%) 4 (12.5%)
9 (12.5%) 7 (17.5%) 2 (6.3%)
Blood tests; median (IQR)
 Lymphocytes (cells/mm3) 2260 (1445−3422.5) 1880 (1000−3360) 2410 (1750−3610) .390
 D-dimer (ng/mL) 725 (442.5−1387) 844 (639−1612.3) 620 (390−1040) .064
 LDH (IU/L) 304 (271−385) 345 (285−404) 284 (270.3−311.8) .038
 Ferritin (ng/mL) 62.5 (39.3−143.3) 112 (38.8−571.5) 45.5 (38−126.8) .274
 CRP (mg/L) 7.45 (0.5−41.8) 7.45 (0.6−56.45) 9.6 (0.5−41.6) .363
 PCT (ng/mL) 0.09 (0.05−0.15) 0.11 (0.07−0.18) 0.05 (0.03−0.11) .018
Lymphopenia, n (%) 20 (32.3%) 14 (40%) 6 (22.2%) .176
Oxygen therapy, n (%)
 No
 Nasal prongs 56 (77.8%) 28 (70%) 28 (87.5%) .093
 Reservoir 16 (22.2%) 12 (30%) 4 (12.5%) .093
 High-flow oxygen therapy 3 (4.2%) 3 (7.5%) 0 .249
 NIVb 1 (1.4%) 1 (2.5%) 0 1.000
1 (1.4%) 1 (2.5%) 0 1.000
Treatment, n (%)
 Antiviral
 Hydroxychloroquine 36 (50%) 24 (60%) 12 (37.5%) .096
 Lopinavir/ritonavir 1 (1.4%) 1 (2.5%) 0 1.000
 Remdesivir 1 (1.4%) 1 (2.5%) 0 1.000
 Antibiotic
 Azithromycin 17 (23.6%) 9 (22.5%) 8 (25%) 1.000
 Other antibiotics 32 (44.4%) 21 (52.5%) 11 (34.4%) .155
 Immunomodulator
 Tocilizumab 2 (2.8%) 2 (5%) 0 .499
 Corticosteroid 1 (1.4%) 1 (2.5%) 0 1.000
 Immunoglobulin 1 (1.4%) 1 (2.5%) 0 1.000
 Antiaggregant
 Acetylsalicylic acid 1 (1.4%) 1 (2.5%) 0 1.000

CRP, C-reactive protein; IQR, interquartile range; LDH, lactate dehydrogenase; NIV, non-invasive mechanical ventilation; PCT, procalcitonin; COVID-19, coronavirus disease caused by SARS-CoV-2.

a

Fisher exact test not applicable, variable with more than 2 categories.