Fig. 1.

The integrin receptor family: Integrin subunits and the known dimers formed. Each connecting line represents one integrin. Although small-molecule ligands have been developed for many subtypes, radiolabeled derivatives thereof were reported only for a fraction of integrins (blue and red lines). "Clinical translation" encompasses all hitherto reported applications of such radiopharmaceuticals in humans, i.e., not only clinical trials but also single cases and small cohorts