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. 2021 Sep;9(17):1374. doi: 10.21037/atm-21-2013

Figure 1.

Figure 1

MiR-552-3p is highly expressed in GBC tissues and CSCs (n=41). (A) The relative miR-552-3p expression levels in GBC tissues and non-tumor adjacent tissues (NATs); (B) the relative expression level of miR-552-3p was detected in 41 patients; (C) the expression of miR-552-3p in spheroids and reattached cells was compared by q-PCR; (D) real-time PCR was used to detect the expression of miR-552-3p in passaged GBC spheroids; (E) real-time PCR was used to analyze the expression of miR-552-3p in CD44+ GBC cells sorted by flow cytometry relative to CD44− GBC cells; (F) real-time PCR was used to analyze the expression of miR-552-3p in CD133+ GBC cells sorted by flow cytometry relative to CD133− GBC cells. *, P<0.05. GBC, gallbladder cancer; CSCs, cancer stem cells; NATs, non-tumor adjacent tissues.