Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep;9(17):1376. doi: 10.21037/atm-21-227

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

2021 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

PMC Copyright notice

Exosomes derived from TNF-α-treated rat NPCs induced NPC apoptosis and repressed IGF-1 expression. (A) Flow cytometry showing the effects of exosomes from TNF-α-treated nucleus pulposus cells (NPCs, TNF-exos) on apoptosis. (B) Western blot analyzing the pro-apoptosis and anti-apoptosis protein markers in NPCs (C) Western blot analyzing the effects of TNF-Exos on insulin-like growth factor 1 (IGF-1) expression. Data are expressed as the mean ± SD, n=3. *P<0.05, **P<0.01 versus the indicated group. TNF, tumor necrosis factor; NPCs, nucleus pulposus cells; SD, standard deviation.