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. 2021 Oct 12;114:79–84. doi: 10.1016/j.ijid.2021.10.012

Table 1.

Demographic and clinical characteristics of COVID-19 patients in melatonin and control groups.

Patient characteristics All patients (n=158) Control group (n=76) Melatonin group (n=82) df P-value
Age (mean±SD) 56.3±7.7 55.7±8.0 56.8±7.5 . 0.393 ͣ
Gender
Male, n (%) 114 (72.2%) 56 (73.7%) 58 (70.7%) 1 0.725°
Female, n (%) 44 (27.8%) 20 (26.3%) 24 (29.3%)
Other comorbidities Hypertension
84 (53.2%) 34 (44.7%) 50 (61.0%) 1 0.055°
Ischemic heart disease 25 (15.8%) 10 (13.2%) 15 (18.3%) 0.394°
47 (29.7%) 22 (28.9%) 25 (30.5%) 0.863°
Diabetes mellitus
Asthma 16 (10.1%) 11 (14.5%) 5 (6.1%) 0.113°

df, degree of freedom; SD, standard deviation; n, number of patients; %, percentage of patients in each group; °, no significant difference (P > 0.05) using Chi-square test; ͣ, no significant difference (P > 0.05) using Mann-Whitney U test