Table 7.
Decrement | Odds Ratios (95% CI) | p-value | ||
---|---|---|---|---|
sOBJ | ||||
baseline1 | 1 z | 1.70 (1.20, 2.42) | 0.003 | |
30 months1 | 1 z | 2.09 (1.44, 3.03) | <0.001 | |
ΔOBJ | ||||
WSD1 | 1 z | 1.20 (0.88, 1.64) | 0.25 | |
LR1,2 | 0.046 SD | 1.06 (0.80, 1.41) | 0.67 | |
LME1,2 | 0.005 SD | 2.02 (1.43, 2.86) | <0.001 |
Note. Odds ratios represent the likelihood of progressing from cognitively unimpaired to MCI given a 1 SD lower performance for each individual method. sOBJ = subtle objective cognitive impairment at a single assessment. ΔOBJ = subtle objective cognitive decline (longitudinal). WSD = within subjects’ standard deviation. LR = annualized change from linear regression model. LME = annualized change from linear mixed effects model.
Reverse scaling applied so that the odds ratios are greater than one.
ΔOBJ-LR and ΔOBJ-LME were scaled by dividing by their standard deviations.