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. Author manuscript; available in PMC: 2021 Oct 12.
Published in final edited form as: J Alzheimers Dis. 2021;83(2):861–877. doi: 10.3233/JAD-210251

Table 7.

Odds ratio with 95% confidence intervals (CI) from conditional logistic regression models for specified unit of decrement in cross-sectional or longitudinal One Card Learning performance with corresponding increases in likelihood of progression to MCI.

Decrement Odds Ratios (95% CI) p-value
sOBJ
 baseline1 1 z 1.70 (1.20, 2.42) 0.003
 30 months1 1 z 2.09 (1.44, 3.03) <0.001
ΔOBJ
 WSD1 1 z 1.20 (0.88, 1.64) 0.25
 LR1,2 0.046 SD 1.06 (0.80, 1.41) 0.67
 LME1,2 0.005 SD 2.02 (1.43, 2.86) <0.001

Note. Odds ratios represent the likelihood of progressing from cognitively unimpaired to MCI given a 1 SD lower performance for each individual method. sOBJ = subtle objective cognitive impairment at a single assessment. ΔOBJ = subtle objective cognitive decline (longitudinal). WSD = within subjects’ standard deviation. LR = annualized change from linear regression model. LME = annualized change from linear mixed effects model.

1

Reverse scaling applied so that the odds ratios are greater than one.

2

ΔOBJ-LR and ΔOBJ-LME were scaled by dividing by their standard deviations.