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. 2021 Sep;9(18):1460. doi: 10.21037/atm-21-4164

Figure 3.

Figure 3

Wog suppressed PC cell stem cell-like transition and mesenchymal transition. Following 0, 25, 50 or 100 µM Wog stimulation, (A) the stem cell-like transition of PANC-1 and SW1990 cells were detected via cell spheres assay (magnification: 100×), (B) the mesenchymal transition of PANC-1 and SW1990 cells were evaluated under a microscope (magnification: 200×), (C,D) the protein levels of CD44, SOX2, N-cad and MMP14 in PANC-1 and SW1990 cells were detected via western blotting. *P<0.05 or **P<0.01 vs. 0 µM Wog stimulation group. PC, pancreatic cancer.