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. 2021 Sep;9(18):1441. doi: 10.21037/atm-21-4192

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2021 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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CALD1 was associated with immune infiltration levels and immune checkpoint blockade target genes. (A) The correlation of CALD1 expression with diverse immune cells infiltration levels in BC from TIMER database. (B) The correlation between CADL1 expression and immune checkpoint inhibitor target genes, including CD274, PDCD1, and CTLA4. (C) PD-L1 surface-antigen detection using flow cytometry. ** vs. Ctrl, P<0.01; ^# vs. NC, P<0.05; ^## vs. NC, P<0.01. BC, bladder cancer; TIMER, Tumor Immune Estimation Resource; NC, non-silencing control.