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. 2021 Sep;9(18):1440. doi: 10.21037/atm-21-4097

Table 2. Prognostic factors for OS in bladder cancer patients after radical cystectomy.

Factors Univariate analysis Multivariate analysis
HR 95% CI P value HR 95% CI P value
Sex 0.67 0.28–1.56 0.35
Age 1.91 1.10–3.34 0.21
BMI 0.89 0.53–1.49 0.67
Smoking 4.85 2.67–8.83 0.01 2.49 1.30–4.78 0.006
Cardiopulmonary disease 1.17 0.65–2.07 0.59
Diabetes mellitus 1.36 0.73–2.53 0.32
Tumor size 1.84 1.10–3.09 0.02 1.54 0.90–2.64 0.11
T stage 7.04 3.32–14.94 0 3.72 1.66–8.32 0.001
N stage 2.50 1.28–4.87 0.007 1.33 0.64–2.77 0.43
M stage 2.98 1.18–7.50 0.02 2.80 1.01–7.77 0.048
Tumor histological types 1.35 0.83–2.19 0.223
Grade 1.58 0.68–3.68 0.28
AGR 0.15 0.075–0.31 0 0.25 0.11–0.55 0.001
NLR 2.79 1.65–4.69 0.001 2.11 1.05–4.24 0.019
PLR 2.04 1.12–3.73 0.019
CAR 4.94 2.85–8.57 0 2.31 1.14–4.71 0.02
Albumin 0.59 0.34–1.02 0.06
Hemoglobin 0.31 0.17–0.55 0 0.78 0.40–1.51 0.46
Neutrophil 1.56 0.93–2.60 0.089

AGR, albumin/globulin ratio; CAR, C-reactive protein/albumin ratio; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio.