Table 3. Prognostic factors for PFS in bladder cancer patients after radical cystectomy.
| Factors | Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | ||
| Sex | 0.53 | 0.22–1.23 | 0.14 | ||||
| Age | 1.51 | 0.91–2.53 | 0.11 | ||||
| BMI | 1.20 | 0.73–1.97 | 0.45 | ||||
| Smoking | 5.38 | 3.57–8.12 | 0.001 | 4.06 | 2.59–6.36 | 0.001 | |
| Cardiopulmonary disease | 1.11 | 0.64–1.94 | 0.702 | ||||
| Diabetes mellitus | 1.50 | 0.82–2.72 | 0.18 | ||||
| Tumor size | 1.73 | 1.03–2.89 | 0.036 | 1.35 | 0.79–2.31 | 0.26 | |
| T stage | 3.94 | 2.21–7.01 | <0.001 | 4.36 | 1.93–9.85 | 0.001 | |
| N stage | 2.47 | 1.24–4.89 | 0.01 | 1.54 | 0.73–3.24 | 0.24 | |
| M stage | 1.86 | 0.67–5.15 | 0.22 | ||||
| Tumor histological types | 1.43 | 0.89–2.32 | 0.14 | ||||
| Grade | 1.87 | 0.80–4.33 | 0.14 | ||||
| AGR | 0.42 | 0.24–0.71 | 0.001 | 0.27 | 0.12–0.62 | 0.002 | |
| CAR | 3.16 | 1.92–5.22 | 0.001 | 2.30 | 1.19–4.42 | 0.013 | |
| NLR | 1.70 | 1.20–2.42 | 0.003 | 1.00 | 0.66–1.52 | 0.01 | |
| PLR | 1.51 | 1.03–2.20 | 0.031 | 0.84 | 0.44–1.63 | 0.62 | |
| Albumin | 0.52 | 0.31–0.89 | 0.019 | 0.91 | 0.44–1.89 | 0.81 | |
| Hemoglobin | 0.41 | 0.24–0.69 | 0.001 | 0.77 | 0.37–1.57 | 0.47 | |
| Neutrophil | 0.833 | 0.50–1.36 | 0.47 | ||||
AGR, albumin/globulin ratio; CAR, C-reactive protein/albumin ratio; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio.